![]() Mishandling of your blood test: It is possible (although unlikely) that your blood specimen was mishandled.Lipidemia: An excess of fat particles (lipids) in your blood can cause a mistakenly high hemoglobin measurement. ![]() Infections: Certain infections, such as cytomegalovirus and pneumonia, can cause red blood cells to clump together, which can make hemoglobin levels appear high.High bilirubin levels could indicate liver disease, gallstones, hemolytic anemia, and Gilbert's syndrome. Bilirubin is the substance that's created when your body breaks down red blood cells. Hyperbilirubinemia: This is characterized by high bilirubin levels.Blood transfusion: The hemoglobin levels from the blood in the transfusion may have been high, thus temporarily giving you high hemoglobin.
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